Good Morning from Bali, Indonesia.
Several months ago I stated in a blog that once they find a drug that works against coronavirus they probably won't have to wait the normal 12 to 18 months to start using it.FDA might grant emergency approval of remdesivir for COVID-19
ByBrian P. Dunleavy
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Multiple studies have yielded mixed results on the effectiveness of Gilead's drug, remdesivir, for the treatment of Covid-19, but a new study announced by the company suggests it could be effective for some patients. File Photo by Terry Schmitt/UPI |
April 29 (UPI) -- The U.S. Food and Drug Administration might grant emergency approval for the antiviral drug remdesivir as a treatment for COVID-19 following new clinical trial results that suggest the drug could help some patients.
The New York Times and CNBC on Wednesday reported the FDA was working with manufacturer Gilead Sciences to make remdesivir available to patients who have COVID-19, the disease caused by the novel coronavirus SARS-CoV-2.
Gilead earlier Wednesday announced preliminary results of a trial with COVID-19 patients, which suggests that at least 50 percent of those treated with a five-day regimen showed improvement. More than half of those enrolled in the study were discharged from the hospital within two weeks of receiving the drug.
The new trial results on remdesivir, a drug originally developed to treat Ebola, appear to contradict those of a trial the World Health Organization posted in error last week. The study was published Wednesday by The Lancet.
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While that study found the drug was safe and adequately tolerated, researchers said it showed minimal benefits over a placebo. The length of time to clinical improvement and risk for death were the same, though remdesivir appeared to shorten the duration of mechanical ventilation required for patients.
Gilead's announcement of results from the large SIMPLE trials, which will eventually enroll 6,000 COVID-19 patients who are on mechanical ventilation at 180 hospitals worldwide, included 397 hospitalized patients with severe illness from the coronavirus.
Participants received 200 milligrams of remdesivir on the first day, followed by 100 mg. daily for five or 10 days, with all doses delivered intravenously.
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The time to clinical improvement for 50 percent of the patients was 10 days in the five-day treatment group and 11 days in the 10-day treatment group. At day 14, 65 percent of the participants in the five-day treatment group and 54 percent in the 10-day treatment group achieved clinical recovery.
Patients who received remdesivir within 10 days of symptom onset had improved outcomes compared with those treated after more than 10 days of symptoms, according to Gilead.
By Day 14, 62 percent of patients treated early were able to be discharged from the hospital, compared with 49 percent of patients who were treated late, the company said.
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"These data are encouraging as they indicate that patients who received a shorter, five-day course of remdesivir experienced similar clinical improvement as patients who received a 10-day treatment course," study co-author Dr. Aruna Subramanian said in a statement released by the company.
"While additional data are still needed, these results help to bring a clearer understanding of how treatment with remdesivir may be optimized, if proven safe and effective," said Subramanian, who is chief of Immunocompromised Host Infectious Diseases at Stanford University School of Medicine.
Gilead on Wednesday also noted that another trial by the National Institute of Allergy and Infectious Diseases met its main efficacy goal. However, it did not elaborate.
Huge Bali Luxury Villas & Estates
Starting at a $6.00 Per Person:
Prices start as low as six dollars per person.Azizah & Lawrence with & staff at the head office, Sanur PT Bali Luxury Villas |
These prices are specifically designed for those who wish to improve their lifestyle while under self-quarantine in Bali in addition to those who wish to escape from places such as Jakarta, Surabaya, and other major cities where coronavirus may get horrific before it's over.
Free Laundry:
Each kitchen has its own large marble and teak kitchen with a full-size refrigerator and four-burner stove plus all the appliances to make your stay comfortable. Remember you won't have to do the dishes most of the time because a housekeeper will take care of that.
Best of all they all have a private swimming pool from 9 m to 14 m in the beachfront estates.
Cancel your current accommodations & Move In.
Fiber Optic Wi-Fi, TV and Telephone:
Award-Winning 24 Hr. Management:
Bali Paradise Beach Estates
Coronavirus Special.
Starting at a $6.00 Per Person:
70 -80 % Discount
The view from this estate
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The Estate:
Other things to note:
Whether you rent one bedroom or four bedrooms you will have private use of the entire four-bedroom estate including a private 14 m swimming pool. The bedrooms you do not rent will be locked.
Beautiful Saba River Only five minutes walk. |
The Owners Lawrence and Notaris/Spouse Azizah at their home at Bali Paradise Beach Estates
Interested parties please contact me. Lawrence, directly at 62-8123814014 Email: lbptbali@gmail.com or our Rentals Manager Yanthi at +62 815-5890-0389 or our Reception at PT Bali Luxury Villas at 62-361-284069
Contact me direct at 62 – 812-381-4014 to confirm. Photos and details at https://www.airbnb.com/rooms/15345034
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If this information was useful to you simply copy this link and send it to your family, friends, clients, and staff so they may also understand this Virus better. If this information was useful to you simply copy this link and send it to your family, friends, clients, and staff so they may also understand this Virus better. https://baliworldnewsviews.blogspot.com/2020/04/bali-is-worlds-most-instagrammed-island.html
Bali Luxury Retirement Villas
2.98 Milyar
The following Information is available on our website:
Features of © Bali Luxury Retirement Villas as low as * $184,888.
•100% legal for foreigners.
• Includes leases totaling 80 yrs.
• Private carport included.
• Private 8 m (27 Ft.) pool** for leisurely laps.
• Only 200 Mtr. To a fabulous beach, restaurants, beach clubs.
• Great investment for you and your heirs.
• Private Housekeepers & drivers, only $200 MTh.
• Healthcare at a fraction of Western costs.
• Brand-new hospital within five minutes.
• Award-winning International Airport 35 min.
• Proximity to Sanur, Ubud, Denpasar.
• Walking distance to affordable restaurants and beach clubs
• Shared low costs of pool man and gardeners.
• Minuscule monthly common area fees.
• Managed by 15-year-old, Hall of Fame award-winning management company.
• *Price of the least expensive villa in U.S.D. after $10,000 Discount for the first two villas only. Subject to change without notice.
• **Eight-meter first-class swimming pool Only U.S.D. $28,888 Extra.
Developed and managed by 14-year-old Hall of Fame award-winning Bali company.
Summary:
Profit Now Move in Later:
Free Stay in Luxury Estate:
Thank you for taking the time out of your busy schedule to review this information and information on the website. If there is any further information we can provide you please do not hesitate to ask.
P.S. We also have several larger villas available from two-bedroom to four-bedroom starting as low as $158,888. www.baliluxuryvillasales.com
If this information was useful to you simply copy this link and send it to your family, friends, clients, and staff so they may also understand this Virus better. If this information was useful to you simply copy this link and send it to your family, friends, clients, and staff so they may also understand this Virus better. https://baliworldnewsviews.blogspot.com/2020/04/bali-is-worlds-most-instagrammed-island.html
Huge 450M2 Estate In Beachfront